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Dr. Qin's Published Works PDF Print E-mail
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Friday, 14 September 2012 20:17

Original Scientific Articles (Published):

  1. Qin K, Wang D-F. Naturally labeled 13C-glucose: use for carbohydrate metabolic studies in pediatric diabetes and obesity. J. Stable Isotope. 1987; 2:33-38.
  2. Cheng K-C, White P.C, Qin K. Molecular cloning and expression of rat liver 3?-hydroxysteroid dehydrogenase. Mol. Endo. 5:823-828, 1991.
  3. Qin K, New MI, Cheng K-C. Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3?-hydroxysteroid dehydrogenase. J. Steroid Biochem. Mol. Biol. 1993; 46:673-679.
  4. Cheng K-C, White PC, Qin K. Distribution and ontogeny of 3?-hydroxysteroid dehydrogenase in the brain. J. Steroid Biochem. Mol. Biol. 1994; 50:85-89.
  5. Qin K, Khanna M, Cheng K-C. Structure of a gene coding for human dihydrodiol dehydrogenase/bile acid-binding protein. Gene. 1994; 149:357-361.
  6. Qin K, Cheng K-C. Structure and tissue-specific expression of the aldo/keto reductase superfamily. Biochemistry. 1994; 33:3223-3228.
  7. Khanna M, Qin K, Klisak I, Belkin S, Sparkes RS, Cheng K-C. Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization. Genomics. 1995; 25:588-590.
  8. Khanna M, Qin K, Cheng K-C. Distribution of 3?-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in human. J. Steroid Biochem. Mol. Biol. 1995; 53:41-46.
  9. Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J. Clin. Endocrinol. Metab. 1995; 80:3689-3698.
  10. Khanna M, Qin K, Wang RW, Cheng K-C. Substrate specificity, gene structure, and tissue-specific distribution of multiple human of 3?-hydroxysteroid dehydrogenase. J. Biol. Chem. 1995; 270:20162-20168.
  11. Carani C, Qin K, Simoni M, Faustini MF, Fustini MF, Serpente S, Boyd J, Korach KS, Simpson ER. Aromatase deficiency in the male. Effect of testosterone and estradiol treatment. N Engl J Med. 1997; 337:91-95.
  12. Qin K, Rosenfield RL. Expression of 17ß-hydroxysteroid dehydrogenase type 5 in human ovary. A pilot study. J Soc Gynecol Investig 2000; 7:61-64.
  13. Nelson VL, Qin K, Rosenfield RL, Wood JR, Penning TM, Legro RS, Strauss JF 3rd, McAllister JM. The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome. J Clin Endocrinol Metab 2001 Dec;86(12):5925-33
  14. Sardani Y, Qin K, Haas M, Aronson AJ, Rosenfield RL. Bartter syndrome complicated by immune complex nephropathy. Case report and literature review. Pediatr Nephrol. 2003 Sep;18(9):913-8. Epub 2003 Jun 26.
  15. Qin K, Rosenfield RL. Characterization of the basal promoter element of the human type 5 17beta-hydroxysteroid dehydrogenase gene. Biochim Biophys Acta 2005; 1728:115-25
  16. Qin K, Ehrmann DA, Cox N, Refetoff S, and Rosenfield RL. Identification of a functional polymorphism of the human type 5 17?-hydroxysteroid dehydrogenase gene associated with polycystic ovary syndrome. J Clin Endocrinol Metab. 2006 Jan;91(1):270-6.
  17. Qin K, Du X, and Rich B. An Alu-mediated rearrangement causing a 3.2 kb deletion and a novel two base pair deletion in AAAS gene as the cause of Triple A syndrome. Mol Genet Metab. 2007 Dec;92(4):359-63.
  18. Du X, Rosenfield RL, Qin K. KLF15 is a Transcriptional Regulator of The Human 17?-Hydroxysteroid Dehydrogenase Type 5 Gene. A potential link between regulation of testosterone production and fat stores in women. J Clin Endocrinol Metab. 2009 Jul;94(7):2594-601.
  19. Deplewski D, Qin K, Ciletti N, Rosenfield RL. Unique mode of lipogenic activation in rat preputial sebocytes. J Nutr Metab. 2011;2011:163631. Epub 2011 Jul 26.
  20. Gregg B, Kociolek LK, Qin K, Rosenfield RL, Yu C. P450c17 Deficiency Caused by Compound Heterozygosity for Two Novel Mutations Presenting as Hypotension in Early Infancy. Horm Res Paediatr. 2011 Aug 4. [Epub ahead of print]
  21. Chen Y, Wang W, Qin K, Dong Z, Xiao Y, Wang D. Identification of two novel CYP17A1 mutations as the cause of 46, XY disorders of sex development in Chinese children. JPEM. 2011 (accepted)


  1. Qin K, Wang D-F, Zeng J-S. Radioimmunoassay of salivary progesterone and its application. Reproduction & Contraception. 1988; 8:3-9.
  2. Simpson ER, Zhano Y, Agarwal VR, Michael MD, Bulun SE, Hinshelwood MM, Graham-Lorence S, Sun T, Fisher CR, Qin K, Mendelson C. Aromatase expression in health and disease. Recent Progress in Hormone Research. 1997; 52:185-214.
  3. Qin K, Rosenfield RL. Role of cytochrome P450c17 in polycystic ovary syndrome. Mol Cell Endocrinol. 1998; 145:111-121.
  4. Rosenfield RL, Qin K. Adrenocortical disorders in infancy and childhood. In: Becker K, Bilezikian J, Bremner W, eds. Principle and Practice of Endocrinology and Metabolism. 3rd. Philadelphia: Lippincott, JB, Ch 83; 2001.
  5. Zouboulis CC, Chen WC, Thornton MJ, Qin K, Rosenfield R.. Sexual hormones in human skin. Horm Metab Res. 2007 Feb;3 9(2):85-95.
  6. Book Review for “Adrenal Disease in Childhood” (C.E. Fluck and W.L. Miller, editors)
  7. Qin K. Genetic Defects of Androgen Resistance. In: Roy E. Weiss and Samuel Refetoff, eds. Genetic Diagnosis of Endocrine Disorders. 1st. Elsevier. Ch 22; 2010.


  1. Rosenfield RL, Qin K. Normal adrenarche. In: Rose B (ed). UpToDate (CD). Wellesley MA: UpToDate, 1998-, (
  2. Rosenfield RL, Qin K. Premature adrenarche. In: Rose B (ed). UpToDate (CD). Wellesley MA: UpToDate, 1998-, (
Last Updated on Friday, 14 September 2012 20:25

Dr. Qin

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